Acetamide, 2-chloro-N-methyl-
2-Chloro-N-methylacetamide
CAS: 96-30-0
Molecular Formula: C3H6ClNO
Acetamide, 2-chloro-N-methyl- - Names and Identifiers
| Name | 2-Chloro-N-methylacetamide |
| Synonyms | OTAVA-BB BB7020410071 chloroacetylmethylamide N-Methylchloroacetamide 2-CHLORO-N-METHYLACETAMIDE N-Methyl-2-chloroacetamide 2-chloro-n-methyl-acetamid N-METHYL-2-CHLOROACETAMIDE 2-Chloro-N-methylacetamide Acetamide, 2-chloro-N-methyl- alpha-Chloro-N-methylacetamide |
| CAS | 96-30-0 |
| EINECS | 202-497-1 |
| InChI | InChI=1/C3H6ClNO/c1-5-3(6)2-4/h2H2,1H3,(H,5,6) |
Acetamide, 2-chloro-N-methyl- - Physico-chemical Properties
| Molecular Formula | C3H6ClNO |
| Molar Mass | 107.54 |
| Density | 1.127±0.06 g/cm3(Predicted) |
| Melting Point | 38-40°C |
| Boling Point | 112-115°C 20mm |
| Flash Point | 110°C |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Vapor Presure | 0.0138mmHg at 25°C |
| Appearance | Solid |
| Color | White to Off-White Low-Melting |
| pKa | 14.38±0.46(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.425 |
| MDL | MFCD00018913 |
Acetamide, 2-chloro-N-methyl- - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R43 - May cause sensitization by skin contact R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36/37 - Wear suitable protective clothing and gloves. S24 - Avoid contact with skin. |
| RTECS | AB5775000 |
| HS Code | 29241990 |
| Hazard Class | IRRITANT |
Acetamide, 2-chloro-N-methyl- - Reference Information
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| Use | 2-chloro-n-methylacetamide, I .e., 2-chloroacetylamine, can be obtained by acylation of Chloroacetyl Chloride and methylamine. 2-chloro-n-methylacetamide can be used in the preparation of O,O-dimethyl-S-(N-methylcarbamoylmethyl) phosphorothioate and lumeperone. |
| preparation | 11.5 (0.145mol) of Chloroacetyl Chloride was added dropwise to 0.58 (mass fraction) of 55 (40% mol) aqueous solution of methylamine and 50ml of water, keep the drop temperature at -20 °c, at -15 °c reaction for 5 hours, after the reaction is finished with dichloromethane extraction three times, dry with anhydrous calcium chloride, the drying agent is filtered off by Suction filtration, and the solvent is removed by rotary evaporation to obtain a colorless solid. The fraction of 84-90 ° C. (vacuum degree of 10mmHg) is 2-chloro-n-methylacetamide, which is collected by vacuum distillation, 13.86g of white crystals were obtained in 88.9% yield; Melting Point: 45-46 °c; 1H NMR (6.61 MHz,CDCl3)δ(ppm): 4.06 (br,1H), (s,2H),2.87(d,3H). |
Last Update：2024-04-09 15:16:53
Supplier List
Spot supply
Product Name: 2-Chloro-N-methylacetamide Request for quotationCAS: 96-30-0
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685
Spot supply
Product Name: 2-Chloro-N-methylacetamide Request for quotationCAS: 96-30-0
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Spot supply
Product Name: 2-Chloro-N-methylacetamide Request for quotationCAS: 96-30-0
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Spot supply
Product Name: Tadalafil Impurity 120 Visit Supplier Webpage Request for quotationCAS: 96-30-0
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: 2-Chloro-N-methylacetamide Visit Supplier Webpage Request for quotationCAS: 96-30-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: 2-Chloro-N-methylacetamide Request for quotationCAS: 96-30-0
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685
Spot supply
Product Name: 2-Chloro-N-methylacetamide Request for quotationCAS: 96-30-0
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Spot supply
Product Name: 2-Chloro-N-methylacetamide Request for quotationCAS: 96-30-0
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Spot supply
Product Name: Tadalafil Impurity 120 Visit Supplier Webpage Request for quotationCAS: 96-30-0
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: 2-Chloro-N-methylacetamide Visit Supplier Webpage Request for quotationCAS: 96-30-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History